We engineer RNA networks that enable living cells to detect intracellular RNA molecules and perform computations.
Our group pursues highly interdisciplinary research at the interfaces of chemistry, biology, and materials science. Much of this work exploits programmable molecular interactions between nucleic acids and proteins to direct the assembly of nanometer-scale organic and inorganic components and to construct information-processing circuitry inside living cells. These efforts have wide-ranging implications for biotechnology, medicine, biosensing, and nanotechnology.
We develop low-cost portable diagnostics that can be used to detect pathogens in low-resource settings.
We develop new antimicrobial materials that are active against broad classes of drug-resistant bacteria and fungi.
We produce and chemically modify two-dimensional materials with novel electronic, optical, and mechanical properties.